A lot of toddlers are fussy about keeping clean - and just as many don't seem to care at all. It's too early to say whether your little guy has a disorder and it's not relevant anyway - you would treat a "disorder" the same way you should treat his desire to be clean: don't rush to clean him up. Don't panic, just because he is panicking. Instead, let him wait a moment or two till you get around to finding a tissue or a towel or whatever you need. Speak slowly and calmly to him. Try to expose him to more and more mess - encourage sandbox play, finger painting, helping you bake and other activities that will cause his hands to become "not clean." You really want him to get used to the sensation and become less worried about it. If he doesn't begin to show some improvement, you can also experiment with the Bach Flower essence called "crab apple." It is for people who have cleanliness issues like your son. Find a book on Bach Flowers or a Bach Flower practitioner to help you with this (see also www.bachflower.com).   Sarah Chana